Efficacy of Lithium Prophylaxis in Bipolar Affective Disorder

نویسندگان

  • Manu R.K. Mathew
  • R. Chandrasekaran
  • S.S. Shreeram
  • I. Anand
چکیده

Forty four patients attending the affective disorder clink at J1PMER Hospital who were on prophylactic lithium for bipolar affective disorder were studied, Intra-individual comparison for severity of illness was made between periods of similar duration with and without lithium prophylaxis. It was found that during lithium prophylaxis patients did significantly better on the following parameters: number of episodes of illness, duration of episodes, hospital admission, neuroleptic dosages and duration of antidepressant treatment. Of the 44 patients included in the study, 45% were good responders, 39% were partial responders and 16% were poor responders. Late age of onset was found to be a significant predictor of good response to lithium.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Comparison of the effect of lithium plus quetiapine with lithium plus risperidone in children and adolescents with bipolar I disorder: a randomized clinical trial

Background: In the treatment of bipolar disorder in youths, often more than one medication should be prescribed. In the current study, we compared the efficacy and tolerability of the combination of lithium and quetiapine with lithium and risperidone in the treatment of manic or mixed episodes in children and adolescents. Methods: Thirty patients (aged 10-18 years) who were hospitalized for ...

متن کامل

The comparative efficacy of carbamazepine low and high serum level and lithium carbonate in the prophylaxis of affective disorders.

The prophylactic efficacy of carbamazepine slow release (CBZ) at ke different blood levels and lithium carbonate slow release (LI) was compared in a retrospective/prospective, randomized, 2-year open trial. 84 patients with a DSM-III-R diagnosis of recurrent affective disorder who had no prophylactic medication in the 2 years preceding the trial (no LI nonresponders), were randomly allocated to...

متن کامل

Pharmacological treatment of bipolar disorder

Bipolar affective disorder, classically characterized by repeated episodes of mania interspersed with periods of depression, is a serious mental illness associated with significant morbidity and mortality. management is aimed at both the rapid treatment of acute episodes and long-term prophylaxis. there continues to be a lack of good-quality research available on which to base treatment regimen...

متن کامل

Lithium in bipolar and other affective disorders: prescribing practice in the UK.

The use of lithium for the treatment of mania, prophylaxis of bipolar disorder and augmentation of antidepressants in treatment-refractory unipolar depression is supported by British Association for Psychopharmacology and National Institute for Health and Clinical Excellence guidelines. We describe prescribing patterns with lithium in a large sample of patients with affective disorders. Data we...

متن کامل

A Comparison of Serum Lithium Levels for Maintenance Therapy of Bipolar Mood Disorder

Numerous studies have been done on using low serum lithium levels for maintenance therapy of bipolar mood disorder over the past 30-40 years. In this study we sought for the most suitable serum lithium level that having longer relapse's interval periods and less side effects as to recommended it as a maintenance serum lithium level. Thus, we studied 90 patients with bipolar mood disorder (accor...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 37  شماره 

صفحات  -

تاریخ انتشار 1995